| Date | Time | HomeTeams | AwayTeams | LevelName |
| 8/21/2025 | 7:00 PM | Barnwell High School | Blackville-hilda High School | 2A |
| 8/21/2025 | 6:00 PM | Carolina High School | Blue Ridge High School | 3A |
| 8/21/2025 | 7:30 PM | Marion High School | Lake View High School | 2A |
| 8/21/2025 | 6:00 PM | South Florence High School | West Florence High School | 4A |
| 8/22/2025 | 7:30 PM | A C Flora High School | Westwood High School | 4A |
| 8/22/2025 | 7:00 PM | Airport High School | May River High School | 4A |
| 8/22/2025 | 7:30 PM | Allendale-fairfax High School | Hunter-Kinard-Tyler Middle High School | 1A |
| 8/22/2025 | 7:30 PM | Ashley Ridge High | Berkeley High School | 5A |
| 8/22/2025 | 7:30 PM | Aynor High School | Aiken High School | 3A |
| 8/22/2025 | 7:30 PM | Baptist Hill High School | CLEAR DOT CHARTER SCHOOL | 1A |
| 8/22/2025 | 7:30 PM | Batesburg-leesville High School | Woodland High School | 2A |
| 8/22/2025 | 7:30 PM | Beaufort High School | Fort Dorchester High School | 4A |
| 8/22/2025 | 7:30 PM | C A Johnson High School | Columbia High School | 2A |
| 8/22/2025 | 7:30 PM | Atlantic Collegiate Academy | Mountain View Preparatory | 2A |
| 8/22/2025 | 7:30 PM | Latta High School | TBA | 2A |
| 8/22/2025 | 7:30 PM | Calhoun Falls High School | Greenwood Christian School | 1A |
| 8/22/2025 | 7:30 PM | Central High School | Lewisville High School | 2A |
| 8/22/2025 | 7:30 PM | Chapin High School | Catawba Ridge High School | 5A |
| 8/22/2025 | 7:30 PM | Chapman High School | D W Daniel High School | 3A |
| 8/22/2025 | 7:30 PM | Military Magnet Academy | North Charleston High School | 1A |
| 8/22/2025 | 7:30 PM | Chesnee High School | Pendleton High School | 2A |
| 8/22/2025 | 7:30 PM | Chesterfield High School | Johnsonville High School | 2A |
| 8/22/2025 | 7:30 PM | Christ Church Episcopal School | Hammond School | 3A |
| 8/22/2025 | 7:30 PM | Colleton County | Hampton County High School | 4A |
| 8/22/2025 | 7:30 PM | Conway High School | Wilson High School | 5A |
| 8/22/2025 | 7:30 PM | Crestwood High School | Manning High School | 4A |
| 8/22/2025 | 7:30 PM | Cross High School | TBA | 1A |
| 8/22/2025 | 7:30 PM | Darlington High School | Lamar High School | 4A |
| 8/22/2025 | 7:30 PM | Denmark-Olar High School | Wagener-Salley High School | 1A |
| 8/22/2025 | 7:30 PM | Easley High School | Pickens High School | 5A |
| 8/22/2025 | 7:30 PM | East Clarendon High School | Scott’s Branch High School | 2A |
| 8/22/2025 | 7:30 PM | Eastside High School | Southside High School | 5A |
| 8/22/2025 | 7:30 PM | Edisto High School | Bamberg-Ehrhardt High School | 2A |
| 8/22/2025 | 7:30 PM | Emerald High School | Ninety Six High School | 4A |
| 8/22/2025 | 7:30 PM | Fort Mill High School | TBA | 5A |
| 8/22/2025 | 7:30 PM | Gaffney High School | TBA | 5A |
| 8/22/2025 | 7:30 PM | Georgetown High School | Kingstree Senior High School | 3A |
| 8/22/2025 | 7:30 PM | Gettys D Broome High School | Belton-honea Path High School | 3A |
| 8/22/2025 | 7:30 PM | Gilbert High School | Lexington High School | 4A |
| 8/22/2025 | 7:30 PM | Goose Creek High School | North Myrtle Beach High School | 5A |
| 8/22/2025 | 7:30 PM | Great Falls High School | North Central High School | 1A |
| 8/22/2025 | 7:30 PM | Green Sea Floyds High School | Loris High School | 1A |
| 8/22/2025 | 7:30 PM | Greenville Sr High School | Dorman High School | 5A |
| 8/22/2025 | 7:30 PM | Greer Senior High School | Boiling Springs High School | 4A |
| 8/22/2025 | 7:30 PM | Hardeeville Junior/Senior High School | Bethune Bowman | 1A |
| 8/22/2025 | 7:30 PM | Hemingway High School | Mullins High School | 1A |
| 8/22/2025 | 7:30 PM | Hillcrest High School | Laurens District High School | 5A |
| 8/22/2025 | 7:30 PM | Hilton Head High School | R B Stall High School | 4A |
| 8/22/2025 | 7:30 PM | James Byrnes High School | T L Hanna High School | 5A |
| 8/22/2025 | 7:30 PM | James Island Charter High School | TBA | 5A |
| 8/22/2025 | 7:30 PM | J L Mann High School | Midland Valley High School | 5A |
| 8/22/2025 | 7:30 PM | Eau Claire High School | Ridgeland Secondary Academy of Excellence | 2A |
| 8/22/2025 | 7:30 PM | Lakewood High School | Sumter High School | 4A |
| 8/22/2025 | 7:30 PM | Lancaster High School | Chester High School | 4A |
| 8/22/2025 | 7:30 PM | Lee Central High | Timberland High School | 2A |
| 8/22/2025 | 7:30 PM | Liberty High School | Fountain Inn High School | 2A |
| 8/22/2025 | 7:30 PM | Lugoff-Elgin High School | Lower Richland High School | 5A |
| 8/22/2025 | 7:30 PM | Marlboro County High School | Lake Marion High School & Technology Center | 3A |
| 8/22/2025 | 7:30 PM | Mc Bee High School | Cheraw Senior High School | 1A |
| 8/22/2025 | 7:30 PM | Dreher High School | W J Keenan High School | 4A |
| 8/22/2025 | 7:30 PM | Myrtle Beach High School | Lake City High School-MI | 4A |
| 8/22/2025 | 7:30 PM | Nation Ford High School | Blythewood High School | 5A |
| 8/22/2025 | 7:30 PM | North Augusta High School | Thomson High School | 4A |
| 8/22/2025 | 7:30 PM | Oceanside Collegiate Academy | Irmo High School | 3A |
| 8/22/2025 | 7:30 PM | Orangeburg-wilkinson High School | Anderson Cavaliers | 3A |
| 8/22/2025 | 7:30 PM | Palmetto High School | Wren High School | 3A |
| 8/22/2025 | 7:30 PM | Pelion High School | Williston-elko High School | 2A |
| 8/22/2025 | 7:30 PM | Philip Simmons High School | Hanahan High School | 3A |
| 8/22/2025 | 7:30 PM | Powdersville High School | Seneca High School | 3A |
| 8/22/2025 | 7:30 PM | Ridge Spring-Monetta High School | Dixie High School | 1A |
| 8/22/2025 | 7:30 PM | Ridge View High School | Fairfield Central High School | 5A |
| 8/22/2025 | 7:30 PM | Riverside High School | Mauldin High School | 5A |
| 8/22/2025 | 7:30 PM | Rock Hill High School | River Bluff High School | 5A |
| 8/22/2025 | 7:30 PM | Saluda High School | Crescent High School | 2A |
| 8/22/2025 | 7:30 PM | Silver Bluff High School | South Aiken High School | 3A |
| 8/22/2025 | 7:30 PM | Southside Christian School | Abbeville High School | 3A |
| 8/22/2025 | 7:30 PM | Spartanburg High School | Northwestern High School | 5A |
| 8/22/2025 | 7:30 PM | Spring Valley High School | Richland Northeast High School | 5A |
| 8/22/2025 | 7:30 PM | Strom Thurmond High School | Mc Cormick High School | 2A |
| 8/22/2025 | 7:30 PM | Summerville High School | Stratford High School | 5A |
| 8/22/2025 | 7:30 PM | Swansea High School | Mid-carolina High School | 3A |
| 8/22/2025 | 7:30 PM | Thornwell School | American Leadership Academy Lexington | 1A |
| 8/22/2025 | 7:30 PM | Union High School | Newberry High School | 3A |
| 8/22/2025 | 7:30 PM | Waccamaw High School | Carvers Bay High School | 3A |
| 8/22/2025 | 7:30 PM | Wade Hampton High School (Greenville) | Travelers Rest High School | 5A |
| 8/22/2025 | 7:30 PM | Walhalla Senior High School | Landrum High School | 3A |
| 8/22/2025 | 7:30 PM | Wando High School | Socastee High School | 5A |
| 8/22/2025 | 7:30 PM | Ware Shoals High School | Blacksburg High School | 1A |
| 8/22/2025 | 7:30 PM | West Ashley High School | TBA | 5A |
| 8/22/2025 | 7:05 PM | West Florence High School | South Florence High School | 5A |
| 8/22/2025 | 7:30 PM | Whale Branch Early College High School | Bluffton High School | 2A |
| 8/22/2025 | 7:30 PM | White Knoll High School | Camden Military Academy High School | 5A |
| 8/22/2025 | 7:30 PM | Whitmire High School | Branchville High SChool | 1A |
| 8/22/2025 | 7:30 PM | Woodruff High School | Clinton High School | 3A |
| 8/22/2025 | 7:30 PM | York Comprehensive High School | Indian Land High School | 4A |
| 8/28/2025 | 7:00 PM | South Carolina S.D. | TBA | 1A |
| 8/28/2025 | 7:30 PM | Williston-elko High School | Barnwell High School | 1A |
| 8/29/2025 | 7:30 PM | A C Flora High School | Chapin High School | 4A |
| 8/29/2025 | 7:30 PM | Aiken High School | Airport High School | 4A |
| 8/29/2025 | 7:30 PM | Allendale-fairfax High School | Hampton County High School | 1A |
| 8/29/2025 | 7:30 PM | Ashley Ridge High | Cane Bay High | 5A |
| 8/29/2025 | 7:30 PM | Bamberg-Ehrhardt High School | Buford High School | 1A |
| 8/29/2025 | 7:30 PM | Batesburg-leesville High School | Wagener-Salley High School | 2A |
| 8/29/2025 | 7:30 PM | Belton-honea Path High School | Greer Senior High School | 3A |
| 8/29/2025 | 7:30 PM | Berkeley High School | TBA | 5A |
| 8/29/2025 | 7:30 PM | Bethune Bowman | Eau Claire High School | 1A |
| 8/29/2025 | 7:30 PM | Bishop England High School | St. John’s High School | 4A |
| 8/29/2025 | 7:30 PM | Blacksburg High School | TBA | 2A |
| 8/29/2025 | 7:30 PM | Bluffton High School | TBA | 4A |
| 8/29/2025 | 7:30 PM | Columbia High School | Pelion High School | 2A |
| 8/29/2025 | 7:30 PM | Branchville High SChool | C A Johnson High School | 1A |
| 8/29/2025 | 7:00 PM | Brookland-Cayce High School | River Bluff High School | 4A |
| 8/29/2025 | 7:30 PM | Latta High School | Marion High School | 2A |
| 8/29/2025 | 7:30 PM | Camden High School | Lugoff-Elgin High School | 3A |
| 8/29/2025 | 7:00 PM | Carolina Forest High School | Hartsville High School | 5A |
| 8/29/2025 | 7:30 PM | Carolina High School | Eastside High School | 3A |
| 8/29/2025 | 7:30 PM | Carvers Bay High School | Kingstree Senior High School | 1A |
| 8/29/2025 | 7:30 PM | Lucy Beckham High School | Philip Simmons High School | 5A |
| 8/29/2025 | 7:30 PM | Academic Magnet High School | Military Magnet Academy | 3A |
| 8/29/2025 | 7:30 PM | Cheraw Senior High School | Marlboro County High School | 3A |
| 8/29/2025 | 7:30 PM | Chester High School | Fort Mill High School | 2A |
| 8/29/2025 | 7:30 PM | Clover High School | Hillcrest High School | 5A |
| 8/29/2025 | 7:30 PM | Conway High School | Loris High School | 5A |
| 8/29/2025 | 7:30 PM | Crescent High School | Palmetto High School | 3A |
| 8/29/2025 | 7:30 PM | D W Daniel High School | Stratford High School | 4A |
| 8/29/2025 | 7:30 PM | Denmark-Olar High School | Swansea High School | 1A |
| 8/29/2025 | 7:30 PM | Dillon High School | Socastee High School | 3A |
| 8/29/2025 | 7:30 PM | Dorman High School | Catawba Ridge High School | 5A |
| 8/29/2025 | 7:30 PM | Dutch Fork High School | Spartanburg High School | 5A |
| 8/29/2025 | 7:30 PM | East Clarendon High School | Ridgeland Secondary Academy of Excellence | 2A |
| 8/29/2025 | 7:30 PM | Edisto High School | Blackville-hilda High School | 2A |
| 8/29/2025 | 7:30 PM | Fairfield Central High School | Union High School | 3A |
| 8/29/2025 | 7:30 PM | Fort Dorchester High School | Goose Creek High School | 5A |
| 8/29/2025 | 7:30 PM | Fox Creek High School | Dixie High School | 3A |
| 8/29/2025 | 7:30 PM | Gaffney High School | J L Mann High School | 5A |
| 8/29/2025 | 7:30 PM | North Charleston High School | Cross High School | 3A |
| 8/29/2025 | 7:30 PM | Georgetown High School | Andrews High School | 3A |
| 8/29/2025 | 7:30 PM | Gettys D Broome High School | Chesnee High School | 3A |
| 8/29/2025 | 7:30 PM | Gilbert High School | Wilson High School | 4A |
| 8/29/2025 | 7:30 PM | Great Falls High School | Chesterfield High School | 1A |
| 8/29/2025 | 7:30 PM | Green Sea Floyds High School | Lamar High School | 1A |
| 8/29/2025 | 7:30 PM | Greenwood High School | Beaufort High School | 5A |
| 8/29/2025 | 7:30 PM | Hanahan High School | Wando High School | 3A |
| 8/29/2025 | 7:30 PM | James Byrnes High School | Irmo High School | 5A |
| 8/29/2025 | 7:30 PM | James Island Charter High School | Hilton Head High School | 5A |
| 8/29/2025 | 7:30 PM | Johnsonville High School | Atlantic Collegiate Academy | 1A |
| 8/29/2025 | 7:30 PM | Lake City High School – SC | Timberland High School | 2A |
| 8/29/2025 | 7:30 PM | Lake Marion High School & Technology Center | Calhoun County High School | 2A |
| 8/29/2025 | 7:30 PM | Lake View High School | Mullins High School | 1A |
| 8/29/2025 | 7:30 PM | Lakewood High School | Westwood High School | 4A |
| 8/29/2025 | 7:30 PM | Lancaster High School | Indian Land High School | 4A |
| 8/29/2025 | 7:30 PM | Landrum High School | Berea High School | 2A |
| 8/29/2025 | 7:30 PM | Laurens District High School | Clinton High School | 4A |
| 8/29/2025 | 7:30 PM | Lee Central High | TBA | 2A |
| 8/29/2025 | 7:30 PM | Lewisville High School | Hunter-Kinard-Tyler Middle High School | 1A |
| 8/29/2025 | 7:30 PM | Lexington High School | North Augusta High School | 5A |
| 8/29/2025 | 7:30 PM | Lower Richland High School | Spring Valley High School | 4A |
| 8/29/2025 | 7:30 PM | Mauldin High School | Boiling Springs High School | 5A |
| 8/29/2025 | 7:30 PM | May River High School | West Ashley High School | 4A |
| 8/29/2025 | 7:30 PM | Midland Valley High School | Blythewood High School | 4A |
| 8/29/2025 | 7:30 PM | Nation Ford High School | York Comprehensive High School | 5A |
| 8/29/2025 | 7:30 PM | Newberry High School | Mid-carolina High School | 3A |
| 8/29/2025 | 7:30 PM | North Central High School | Mc Bee High School | 2A |
| 8/29/2025 | 7:30 PM | North Myrtle Beach High School | Darlington High School | 5A |
| 8/29/2025 | 7:30 PM | Northwestern High School | Ridge View High School | 5A |
| 8/29/2025 | 7:30 PM | Ninety Six High School | Ware Shoals High School | 2A |
| 8/29/2025 | 7:30 PM | Orangeburg-wilkinson High School | Hemingway High School | 3A |
| 8/29/2025 | 7:30 PM | American Leadership Academy Lexington | Camden Military Academy High School | 1A |
| 8/29/2025 | 7:30 PM | Pendleton High School | W J Keenan High School | 3A |
| 8/29/2025 | 7:30 PM | Pickens High School | Walhalla Senior High School | 4A |
| 8/29/2025 | 7:30 PM | Richland Northeast High School | Crestwood High School | 4A |
| 8/29/2025 | 7:30 PM | Ridge Spring-Monetta High School | Saluda High School | 1A |
| 8/29/2025 | 7:30 PM | Riverside High School | Greenville Sr High School | 5A |
| 8/29/2025 | 7:30 PM | Scott’s Branch High School | Manning High School | 1A |
| 8/29/2025 | 7:30 PM | Seneca High School | Woodmont High School | 4A |
| 8/29/2025 | 7:30 PM | South Aiken High School | Lakeside High School | 4A |
| 8/29/2025 | 7:30 PM | South Pointe High School | Rock Hill High School | 4A |
| 8/29/2025 | 7:30 PM | Southside Christian School | Mountain View Preparatory | 3A |
| 8/29/2025 | 7:30 PM | Southside High School | Liberty High School | 4A |
| 8/29/2025 | 7:30 PM | St. James High School | Aynor High School | 5A |
| 8/29/2025 | 7:30 PM | St. Joseph’s Catholic School | Chapman High School | 3A |
| 8/29/2025 | 7:30 PM | Strom Thurmond High School | Silver Bluff High School | 2A |
| 8/29/2025 | 7:30 PM | Summerville High School | South Florence High School | 5A |
| 8/29/2025 | 7:30 PM | Sumter High School | TBA | 5A |
| 8/29/2025 | 7:30 PM | Travelers Rest High School | Emerald High School | 4A |
| 8/29/2025 | 7:30 PM | Waccamaw High School | Hannah-pamplico High School | 3A |
| 8/29/2025 | 7:30 PM | Wade Hampton High School (Greenville) | Blue Ridge High School | 5A |
| 8/29/2025 | 7:30 PM | West Florence High School | Myrtle Beach High School | 5A |
| 8/29/2025 | 7:30 PM | West Oak High School | CLEAR DOT CHARTER SCHOOL | 3A |
| 8/29/2025 | 7:30 PM | Whale Branch Early College High School | Hardeeville Junior/Senior High School | 2A |
| 8/29/2025 | 7:30 PM | Whitmire High School | TBA | 1A |
| 8/29/2025 | 7:30 PM | Woodland High School | Colleton County | 2A |
| 8/29/2025 | 7:30 PM | Woodruff High School | Fountain Inn High School | 3A |
| 8/29/2025 | 7:30 PM | Wren High School | Easley High School | 4A |
| 9/4/2025 | 7:00 PM | South Carolina S.D. | TBA | 1A |
| 9/4/2025 | 7:30 PM | Wando High School | Ashley Ridge High | 5A |
| 9/5/2025 | 7:30 PM | Aiken High School | Hilton Head High School | 4A |
| 9/5/2025 | 7:30 PM | Allendale-fairfax High School | Great Falls High School | 1A |
| 9/5/2025 | 7:30 PM | Andrews High School | Carvers Bay High School | 2A |
| 9/5/2025 | 7:30 PM | Bamberg-Ehrhardt High School | Barnwell High School | 1A |
| 9/5/2025 | 7:30 PM | Baptist Hill High School | North Charleston High School | 1A |
| 9/5/2025 | 7:30 PM | Batesburg-leesville High School | Abbeville High School | 2A |
| 9/5/2025 | 7:30 PM | Battery Creek High School | W J Keenan High School | 3A |
| 9/5/2025 | 7:30 PM | Beaufort High School | Philip Simmons High School | 4A |
| 9/5/2025 | 7:30 PM | Berea High School | Carolina High School | 4A |
| 9/5/2025 | 7:30 PM | Bishop England High School | Hanahan High School | 4A |
| 9/5/2025 | 7:30 PM | Blackville-hilda High School | TBA | 1A |
| 9/5/2025 | 7:30 PM | Blue Ridge High School | TBA | 4A |
| 9/5/2025 | 7:30 PM | Bluffton High School | Savannah Country Day School | 4A |
| 9/5/2025 | 7:30 PM | Blythewood High School | Fort Mill High School | 5A |
| 9/5/2025 | 7:30 PM | Boiling Springs High School | Chapman High School | 5A |
| 9/5/2025 | 7:30 PM | C A Johnson High School | Fairfield Central High School | 2A |
| 9/5/2025 | 7:30 PM | Branchville High SChool | Williston-elko High School | 1A |
| 9/5/2025 | 7:30 PM | Atlantic Collegiate Academy | Lewisville High School | 2A |
| 9/5/2025 | 7:30 PM | Buford High School | Highland School of Technology | 2A |
| 9/5/2025 | 7:30 PM | Burke High School | Denmark-Olar High School | 1A |
| 9/5/2025 | 7:30 PM | Calhoun County High School | Edisto High School | 1A |
| 9/5/2025 | 7:30 PM | Calhoun Falls High School | Thornwell School | 1A |
| 9/5/2025 | 7:30 PM | Cane Bay High | West Ashley High School | 5A |
| 9/5/2025 | 7:30 PM | Catawba Ridge High School | Chester High School | 4A |
| 9/5/2025 | 7:30 PM | Lucy Beckham High School | St. James High School | 5A |
| 9/5/2025 | 7:30 PM | Central High School | Lamar High School | 2A |
| 9/5/2025 | 7:30 PM | Chapin High School | Spring Valley High School | 5A |
| 9/5/2025 | 7:30 PM | R B Stall High School | Academic Magnet High School | 5A |
| 9/5/2025 | 7:30 PM | Cheraw Senior High School | Conway High School | 4A |
| 9/5/2025 | 7:30 PM | Chesterfield High School | Lee Central High | 2A |
| 9/5/2025 | 7:30 PM | Christ Church Episcopal School | Riverside High School | 3A |
| 9/5/2025 | 7:30 PM | Clinton High School | Newberry High School | 3A |
| 9/5/2025 | 7:30 PM | Colleton County | Lower Richland High School | 4A |
| 9/5/2025 | 7:30 PM | Cross High School | Timberland High School | 1A |
| 9/5/2025 | 7:30 PM | D W Daniel High School | J L Mann High School | 4A |
| 9/5/2025 | 7:30 PM | Dillon High School | Wilson High School | 3A |
| 9/5/2025 | 7:30 PM | Dixie High School | Southside High School | 1A |
| 9/5/2025 | 7:30 PM | Dorman High School | Greenwood High School | 5A |
| 9/5/2025 | 7:30 PM | Dutch Fork High School | Ridge View High School | 5A |
| 9/5/2025 | 7:30 PM | Easley High School | Wade Hampton High School (Greenville) | 5A |
| 9/5/2025 | 7:30 PM | Emerald High School | Woodruff High School | 4A |
| 9/5/2025 | 7:30 PM | Fountain Inn High School | Mauldin High School | 4A |
| 9/5/2025 | 7:30 PM | Fox Creek High School | TBA | 3A |
| 9/5/2025 | 7:30 PM | Goose Creek High School | James Island Charter High School | 5A |
| 9/5/2025 | 7:30 PM | Greenville Sr High School | Gaffney High School | 5A |
| 9/5/2025 | 7:30 PM | Hampton County High School | Silver Bluff High School | 2A |
| 9/5/2025 | 7:30 PM | Hardeeville Junior/Senior High School | East Clarendon High School | 1A |
| 9/5/2025 | 7:30 PM | Hartsville High School | Camden High School | 4A |
| 9/5/2025 | 7:30 PM | Hillcrest High School | Greer Senior High School | 5A |
| 9/5/2025 | 7:30 PM | Indian Land High School | Andrew Jackson High School | 5A |
| 9/5/2025 | 7:30 PM | Irmo High School | TBA | 5A |
| 9/5/2025 | 7:30 PM | Johnsonville High School | Georgetown High School | 1A |
| 9/5/2025 | 7:30 PM | Eau Claire High School | Greenwood Christian School | 2A |
| 9/5/2025 | 7:30 PM | Kingstree Senior High School | Crestwood High School | 2A |
| 9/5/2025 | 7:30 PM | Lake City High School – SC | May River High School | 2A |
| 9/5/2025 | 7:30 PM | Laurens District High School | Belton-honea Path High School | 4A |
| 9/5/2025 | 7:30 PM | Lexington High School | Midland Valley High School | 5A |
| 9/5/2025 | 7:30 PM | Lugoff-Elgin High School | Darlington High School | 5A |
| 9/5/2025 | 7:30 PM | Manning High School | Lake Marion High School & Technology Center | 2A |
| 9/5/2025 | 7:30 PM | Marion High School | West Florence High School | 2A |
| 9/5/2025 | 7:30 PM | Marlboro County High School | Gray Collegiate Academy | 3A |
| 9/5/2025 | 7:30 PM | Mc Bee High School | TBA | 1A |
| 9/5/2025 | 7:30 PM | Mc Cormick High School | Washington-wilkes High School | 1A |
| 9/5/2025 | 7:30 PM | Dreher High School | Lakewood High School | 4A |
| 9/5/2025 | 7:30 PM | Mid-carolina High School | Whitmire High School | 2A |
| 9/5/2025 | 7:30 PM | Mountain View Preparatory | St Josephs Catholic School | 3A |
| 9/5/2025 | 7:30 PM | Mullins High School | Green Sea Floyds High School | 2A |
| 9/5/2025 | 7:30 PM | Myrtle Beach High School | TBA | 4A |
| 9/5/2025 | 7:30 PM | North Central High School | Columbia High School | 2A |
| 9/5/2025 | 7:30 PM | North Myrtle Beach High School | West Brunswick High School | 5A |
| 9/5/2025 | 7:30 PM | Oceanside Collegiate Academy | TBA | 3A |
| 9/5/2025 | 7:30 PM | Wagener-Salley High School | Swansea High School | 1A |
| 9/5/2025 | 7:30 PM | Orangeburg-wilkinson High School | Airport High School | 3A |
| 9/5/2025 | 7:30 PM | Palmetto High School | Travelers Rest High School | 3A |
| 9/5/2025 | 7:30 PM | American Leadership Academy Lexington | CLEAR DOT CHARTER SCHOOL | 1A |
| 9/5/2025 | 7:30 PM | Pendleton High School | Woodmont High School | 3A |
| 9/5/2025 | 7:30 PM | Pickens High School | Liberty High School | 4A |
| 9/5/2025 | 7:30 PM | Powdersville High School | Wren High School | 3A |
| 9/5/2025 | 7:30 PM | Ridgeland Secondary Academy of Excellence | Whale Branch Early College High School | 1A |
| 9/5/2025 | 7:30 PM | River Bluff High School | Nation Ford High School | 5A |
| 9/5/2025 | 7:30 PM | Rock Hill High School | Lancaster High School | 5A |
| 9/5/2025 | 7:30 PM | Scott’s Branch High School | Hemingway High School | 1A |
| 9/5/2025 | 7:30 PM | Socastee High School | AYNOR HIGH | 5A |
| 9/5/2025 | 7:30 PM | South Aiken High School | North Augusta High School | 4A |
| 9/5/2025 | 7:30 PM | South Florence High School | Northwestern High School | 4A |
| 9/5/2025 | 7:30 PM | South Pointe High School | West Charlotte High School | 4A |
| 9/5/2025 | 7:30 PM | Southside Christian School | A C Flora High School | 3A |
| 9/5/2025 | 7:30 PM | Spartanburg High School | Gettys D Broome High School | 5A |
| 9/5/2025 | 7:30 PM | St. John’s High School | First Baptist Church School | 1A |
| 9/5/2025 | 7:30 PM | Stratford High School | Fort Dorchester High School | 5A |
| 9/5/2025 | 7:30 PM | Summerville High School | Berkeley High School | 5A |
| 9/5/2025 | 7:30 PM | Walhalla Senior High School | Chesnee High School | 3A |
| 9/5/2025 | 7:30 PM | Ware Shoals High School | Landrum High School | 1A |
| 9/5/2025 | 7:30 PM | West Oak High School | Seneca High School | 3A |
| 9/5/2025 | 7:30 PM | Westside High School | T L Hanna High School | 4A |
| 9/5/2025 | 7:30 PM | Westwood High School | Richland Northeast High School | 4A |
| 9/5/2025 | 7:30 PM | White Knoll High School | Brookland-Cayce High School | 5A |
| 9/5/2025 | 7:30 PM | Woodland High School | Bethune Bowman | 2A |
| 9/5/2025 | 7:30 PM | York Comprehensive High School | Union High School | 4A |
| 9/11/2025 | 6:00 PM | North Central High School | Mid-carolina High School | 2A |
| 9/12/2025 | 7:30 PM | Abbeville High School | Ninety Six High School | 1A |
| 9/12/2025 | 7:30 PM | Aiken High School | Lugoff-Elgin High School | 4A |
| 9/12/2025 | 7:30 PM | Andrew Jackson High School | Andrews High School | 2A |
| 9/12/2025 | 7:30 PM | Ashley Ridge High | Oceanside Collegiate Academy | 5A |
| 9/12/2025 | 7:30 PM | Aynor High School | Green Sea Floyds High School | 3A |
| 9/12/2025 | 7:30 PM | Battery Creek High School | Bethune Bowman | 3A |
| 9/12/2025 | 7:30 PM | Belton-honea Path High School | Westside High School | 3A |
| 9/12/2025 | 7:30 PM | Berea High School | Southside High School | 4A |
| 9/12/2025 | 7:30 PM | Berkeley High School | West Ashley High School | 5A |
| 9/12/2025 | 7:30 PM | Bishop England High School | Dreher High School | 4A |
| 9/12/2025 | 7:30 PM | Blue Ridge High School | Eastside High School | 4A |
| 9/12/2025 | 7:30 PM | Blythewood High School | W J Keenan High School | 5A |
| 9/12/2025 | 7:30 PM | Columbia High School | Great Falls High School | 2A |
| 9/12/2025 | 7:00 PM | Brookland-Cayce High School | May River High School | 4A |
| 9/12/2025 | 7:30 PM | Buford High School | Mc Bee High School | 2A |
| 9/12/2025 | 7:30 PM | Calhoun County High School | Bamberg-Ehrhardt High School | 1A |
| 9/12/2025 | 7:30 PM | Carolina High School | Fountain Inn High School | 3A |
| 9/12/2025 | 7:30 PM | Central High School | TBA | 2A |
| 9/12/2025 | 7:30 PM | Academic Magnet High School | Baptist Hill High School | 3A |
| 9/12/2025 | 7:30 PM | Chesnee High School | TBA | 2A |
| 9/12/2025 | 7:30 PM | Chester High School | Saluda High School | 2A |
| 9/12/2025 | 7:30 PM | Chesterfield High School | C A Johnson High School | 2A |
| 9/12/2025 | 7:30 PM | Clinton High School | Chapman High School | 3A |
| 9/12/2025 | 7:30 PM | Clover High School | York Comprehensive High School | 5A |
| 9/12/2025 | 7:30 PM | Colleton County | R B Stall High School | 4A |
| 9/12/2025 | 7:30 PM | Crescent High School | Mountain View Preparatory | 3A |
| 9/12/2025 | 7:30 PM | Cross High School | Lake Marion High School & Technology Center | 1A |
| 9/12/2025 | 7:30 PM | Darlington High School | Cheraw Senior High School | 4A |
| 9/12/2025 | 7:30 PM | Denmark-Olar High School | Hunter-Kinard-Tyler Middle High School | 1A |
| 9/12/2025 | 7:30 PM | Dixie High School | TBA | 1A |
| 9/12/2025 | 7:30 PM | Fairfield Central High School | Lewisville High School | 2A |
| 9/12/2025 | 7:30 PM | Fort Dorchester High School | South Florence High School | 5A |
| 9/12/2025 | 7:30 PM | Fort Mill High School | Lancaster High School | 5A |
| 9/12/2025 | 7:30 PM | North Charleston High School | St. John’s High School | 2A |
| 9/12/2025 | 7:30 PM | Georgetown High School | Carvers Bay High School | 3A |
| 9/12/2025 | 7:30 PM | Gettys D Broome High School | Emerald High School | 3A |
| 9/12/2025 | 7:30 PM | Goose Creek High School | Beaufort High School | 5A |
| 9/12/2025 | 7:30 PM | Gray Collegiate Academy | Dutch Fork High School | 4A |
| 9/12/2025 | 7:30 PM | Greenwood High School | Lexington High School | 5A |
| 9/12/2025 | 7:30 PM | Greer Senior High School | James Byrnes High School | 4A |
| 9/12/2025 | 7:30 PM | Hampton County High School | Bluffton High School | 2A |
| 9/12/2025 | 7:30 PM | Hanahan High School | Lucy Beckham High School | 3A |
| 9/12/2025 | 7:30 PM | Hannah-pamplico High School | TBA | 1A |
| 9/12/2025 | 7:30 PM | Hartsville High School | Rock Hill High School | 4A |
| 9/12/2025 | 7:30 PM | Hemingway High School | Burke High School | 1A |
| 9/12/2025 | 7:30 PM | Hilton Head High School | Hardeeville Junior/Senior High School | 4A |
| 9/12/2025 | 7:30 PM | Irmo High School | Carolina Forest High School | 5A |
| 9/12/2025 | 7:30 PM | James Island Charter High School | Cane Bay High | 5A |
| 9/12/2025 | 7:30 PM | Johnsonville High School | Waccamaw High School | 1A |
| 9/12/2025 | 7:30 PM | Lake View High School | Scott’s Branch High School | 1A |
| 9/12/2025 | 7:30 PM | Lakewood High School | East Clarendon High School | 4A |
| 9/12/2025 | 7:30 PM | Lamar High School | Lake City High School – SC | 1A |
| 9/12/2025 | 7:30 PM | Landrum High School | Asheville Christian Academy | 2A |
| 9/12/2025 | 7:30 PM | Laurens District High School | A C Flora High School | 4A |
| 9/12/2025 | 7:30 PM | Liberty High School | Palmetto High School | 2A |
| 9/12/2025 | 7:30 PM | Loris High School | North Myrtle Beach High School | 3A |
| 9/12/2025 | 7:30 PM | Lower Richland High School | Batesburg-leesville High School | 4A |
| 9/12/2025 | 7:30 PM | Marion High School | Dillon High School | 2A |
| 9/12/2025 | 7:30 PM | Marlboro County High School | Conway High School | 3A |
| 9/12/2025 | 7:30 PM | Mc Cormick High School | Fox Creek High School | 1A |
| 9/12/2025 | 7:30 PM | Mid-carolina High School | North Central High School | 2A |
| 9/12/2025 | 7:30 PM | Mullins High School | Latta High School | 2A |
| 9/12/2025 | 7:30 PM | North Augusta High School | Strom Thurmond High School | 4A |
| 9/12/2025 | 7:30 PM | Northwestern High School | South Point High School | 5A |
| 9/12/2025 | 7:30 PM | Wagener-Salley High School | Allendale-fairfax High School | 1A |
| 9/12/2025 | 7:30 PM | Orangeburg-wilkinson High School | Edisto High School | 3A |
| 9/12/2025 | 7:30 PM | American Leadership Academy Lexington | Ridge Spring-Monetta High School | 1A |
| 9/12/2025 | 7:30 PM | Pendleton High School | Powdersville High School | 3A |
| 9/12/2025 | 7:30 PM | Philip Simmons High School | Military Magnet Academy | 3A |
| 9/12/2025 | 7:30 PM | Richland Northeast High School | Nation Ford High School | 4A |
| 9/12/2025 | 7:30 PM | Ridge View High School | Camden High School | 5A |
| 9/12/2025 | 7:30 PM | Ridgeland Secondary Academy of Excellence | Manning High School | 1A |
| 9/12/2025 | 7:30 PM | River Bluff High School | Gilbert High School | 5A |
| 9/12/2025 | 7:30 PM | Seneca High School | Walhalla Senior High School | 4A |
| 9/12/2025 | 7:30 PM | Silver Bluff High School | Blackville-hilda High School | 3A |
| 9/12/2025 | 7:30 PM | Socastee High School | Stratford High School | 5A |
| 9/12/2025 | 7:30 PM | South Aiken High School | Barnwell High School | 4A |
| 9/12/2025 | 7:30 PM | Spring Valley High School | Catawba Ridge High School | 5A |
| 9/12/2025 | 7:30 PM | St. Joseph’s Catholic School | Pickens High School | 3A |
| 9/12/2025 | 7:30 PM | Sumter High School | Crestwood High School | 5A |
| 9/12/2025 | 7:30 PM | Swansea High School | Pelion High School | 3A |
| 9/12/2025 | 7:30 PM | T L Hanna High School | Wren High School | 5A |
| 9/12/2025 | 7:30 PM | Timberland High School | Kingstree Senior High School | 2A |
| 9/12/2025 | 7:30 PM | Union High School | Blacksburg High School | 3A |
| 9/12/2025 | 7:30 PM | Wando High School | St. James High School | 5A |
| 9/12/2025 | 7:30 PM | West Oak High School | TBA | 3A |
| 9/12/2025 | 7:30 PM | Westwood High School | Airport High School | 4A |
| 9/12/2025 | 7:30 PM | Williston-elko High School | TBA | 1A |
| 9/12/2025 | 7:30 PM | Wilson High School | West Florence High School | 4A |
| 9/12/2025 | 7:30 PM | Woodland High School | Whale Branch Early College High School | 2A |
| 9/12/2025 | 7:30 PM | Woodmont High School | Woodruff High School | 5A |
| 9/18/2025 | 7:30 PM | Chesnee High School | Woodruff High School | 2A |
| 9/19/2025 | 7:30 PM | A C Flora High School | South Pointe High School | 4A |
| 9/19/2025 | 7:30 PM | Allendale-fairfax High School | C A Johnson High School | 1A |
| 9/19/2025 | 7:30 PM | Andrew Jackson High School | Lewisville High School | 2A |
| 9/19/2025 | 7:30 PM | Andrews High School | Waccamaw High School | 2A |
| 9/19/2025 | 7:30 PM | Bamberg-Ehrhardt High School | Woodland High School | 1A |
| 9/19/2025 | 7:30 PM | Baptist Hill High School | Bethune Bowman | 1A |
| 9/19/2025 | 7:30 PM | Barnwell High School | Swansea High School | 2A |
| 9/19/2025 | 7:30 PM | Beaufort High School | Battery Creek High School | 4A |
| 9/19/2025 | 7:30 PM | Belton-honea Path High School | Palmetto High School | 3A |
| 9/19/2025 | 7:30 PM | Blacksburg High School | Central High School | 2A |
| 9/19/2025 | 7:30 PM | Blackville-hilda High School | Denmark-Olar High School | 1A |
| 9/19/2025 | 7:30 PM | Blythewood High School | Westwood High School | 5A |
| 9/19/2025 | 7:30 PM | Columbia High School | Wagener-Salley High School | 2A |
| 9/19/2025 | 7:30 PM | Atlantic Collegiate Academy | Mullins High School | 2A |
| 9/19/2025 | 7:30 PM | Buford High School | Great Falls High School | 2A |
| 9/19/2025 | 7:30 PM | Burke High School | Ridgeland Secondary Academy of Excellence | 1A |
| 9/19/2025 | 7:30 PM | Calhoun County High School | Batesburg-leesville High School | 1A |
| 9/19/2025 | 7:30 PM | Cane Bay High | White Knoll High School | 5A |
| 9/19/2025 | 7:00 PM | Carolina Forest High School | Ashley Ridge High | 5A |
| 9/19/2025 | 7:30 PM | Carvers Bay High School | Hannah-pamplico High School | 1A |
| 9/19/2025 | 7:30 PM | Catawba Ridge High School | Fort Mill High School | 4A |
| 9/19/2025 | 7:30 PM | Lucy Beckham High School | Bluffton High School | 5A |
| 9/19/2025 | 7:30 PM | Chapin High School | Summerville High School | 5A |
| 9/19/2025 | 7:30 PM | Chapman High School | Christ Church Episcopal School | 3A |
| 9/19/2025 | 7:30 PM | North Charleston High School | R B Stall High School | 3A |
| 9/19/2025 | 7:30 PM | Chester High School | Union High School | 2A |
| 9/19/2025 | 7:30 PM | Chesterfield High School | Mc Bee High School | 2A |
| 9/19/2025 | 7:30 PM | Clinton High School | D W Daniel High School | 3A |
| 9/19/2025 | 7:30 PM | Conway High School | Aynor High School | 5A |
| 9/19/2025 | 7:30 PM | Darlington High School | Lower Richland High School | 4A |
| 9/19/2025 | 7:30 PM | Dillon High School | Hartsville High School | 3A |
| 9/19/2025 | 7:30 PM | Dorman High School | Riverside High School | 5A |
| 9/19/2025 | 7:30 PM | Eastside High School | Spartanburg High School | 5A |
| 9/19/2025 | 7:30 PM | Emerald High School | Strom Thurmond High School | 4A |
| 9/19/2025 | 7:30 PM | Fountain Inn High School | St Josephs Catholic School | 4A |
| 9/19/2025 | 7:30 PM | Gaffney High School | Boiling Springs High School | 5A |
| 9/19/2025 | 7:30 PM | Military Magnet Academy | Cross High School | 1A |
| 9/19/2025 | 7:30 PM | Green Sea Floyds High School | Latta High School | 1A |
| 9/19/2025 | 7:30 PM | Greer Senior High School | Berea High School | 4A |
| 9/19/2025 | 7:30 PM | Hampton County High School | Hilton Head High School | 2A |
| 9/19/2025 | 7:30 PM | Hanahan High School | Timberland High School | 3A |
| 9/19/2025 | 7:30 PM | Hardeeville Junior/Senior High School | Lee Central High | 1A |
| 9/19/2025 | 7:30 PM | Indian Land High School | Parkwood High School | 5A |
| 9/19/2025 | 7:30 PM | James Byrnes High School | Wade Hampton High School (Greenville) | 5A |
| 9/19/2025 | 7:30 PM | J L Mann High School | Easley High School | 5A |
| 9/19/2025 | 7:30 PM | W J Keenan High School | Orangeburg-wilkinson High School | 3A |
| 9/19/2025 | 7:00 PM | Lake City High School – SC | East Clarendon High School | 2A |
| 9/19/2025 | 7:30 PM | Lake Marion High School & Technology Center | Hunter-Kinard-Tyler Middle High School | 2A |
| 9/19/2025 | 7:30 PM | Lake View High School | Johnsonville High School | 1A |
| 9/19/2025 | 7:30 PM | Lakewood High School | Wilson High School | 4A |
| 9/19/2025 | 7:30 PM | Lamar High School | North Central High School | 1A |
| 9/19/2025 | 7:30 PM | Liberty High School | Walhalla Senior High School | 2A |
| 9/19/2025 | 7:30 PM | Loris High School | Socastee High School | 3A |
| 9/19/2025 | 7:30 PM | Marion High School | Kingstree Senior High School | 2A |
| 9/19/2025 | 7:30 PM | Marlboro County High School | North Myrtle Beach High School | 3A |
| 9/19/2025 | 7:30 PM | Mauldin High School | Hillcrest High School | 5A |
| 9/19/2025 | 7:30 PM | Mc Cormick High School | Edisto High School | 1A |
| 9/19/2025 | 7:30 PM | Dreher High School | York Comprehensive High School | 4A |
| 9/19/2025 | 7:30 PM | Midland Valley High School | Gray Collegiate Academy | 4A |
| 9/19/2025 | 7:30 PM | Myrtle Beach High School | Irmo High School | 4A |
| 9/19/2025 | 7:30 PM | Nation Ford High School | Northwestern High School | 5A |
| 9/19/2025 | 7:30 PM | Newberry High School | Fairfield Central High School | 3A |
| 9/19/2025 | 7:30 PM | North Augusta High School | Gilbert High School | 4A |
| 9/19/2025 | 7:30 PM | Oceanside Collegiate Academy | Dutch Fork High School | 3A |
| 9/19/2025 | 7:30 PM | Ninety Six High School | Crescent High School | 2A |
| 9/19/2025 | 7:30 PM | Pelion High School | Mid-carolina High School | 2A |
| 9/19/2025 | 7:30 PM | Philip Simmons High School | Whale Branch Early College High School | 3A |
| 9/19/2025 | 7:30 PM | Pickens High School | Blue Ridge High School | 4A |
| 9/19/2025 | 7:30 PM | Powdersville High School | Gettys D Broome High School | 3A |
| 9/19/2025 | 7:30 PM | Richland Northeast High School | Camden High School | 4A |
| 9/19/2025 | 7:30 PM | Ridge Spring-Monetta High School | TBA | 1A |
| 9/19/2025 | 7:30 PM | River Bluff High School | Cheraw Senior High School | 5A |
| 9/19/2025 | 7:30 PM | Rock Hill High School | Clover High School | 5A |
| 9/19/2025 | 7:30 PM | Saluda High School | Southside Christian School | 2A |
| 9/19/2025 | 7:30 PM | Scott’s Branch High School | Branchville High SChool | 1A |
| 9/19/2025 | 7:30 PM | Seneca High School | Travelers Rest High School | 4A |
| 9/19/2025 | 7:30 PM | Silver Bluff High School | TBA | 3A |
| 9/19/2025 | 7:30 PM | South Aiken High School | Brookland-Cayce High School | 4A |
| 9/19/2025 | 7:30 PM | South Florence High School | Crestwood High School | 4A |
| 9/19/2025 | 7:30 PM | Southside High School | Carolina High School | 4A |
| 9/19/2025 | 7:30 PM | St. James High School | James Island Charter High School | 5A |
| 9/19/2025 | 7:30 PM | St. John’s High School | Academic Magnet High School | 1A |
| 9/19/2025 | 7:30 PM | Stratford High School | Colleton County | 5A |
| 9/19/2025 | 7:30 PM | Sumter High School | Spring Valley High School | 5A |
| 9/19/2025 | 7:30 PM | T L Hanna High School | Greenwood High School | 5A |
| 9/19/2025 | 7:30 PM | West Ashley High School | Wando High School | 5A |
| 9/19/2025 | 7:30 PM | West Florence High School | Lugoff-Elgin High School | 5A |
| 9/19/2025 | 7:30 PM | West Oak High School | Landrum High School | 3A |
| 9/19/2025 | 7:30 PM | Woodmont High School | Greenville Sr High School | 5A |
| 9/19/2025 | 7:30 PM | Woodruff High School | Chesnee High School | 3A |
| 9/25/2025 | 6:00 PM | Chester High School | W J Keenan High School | 2A |
| 9/26/2025 | 7:30 PM | Airport High School | South Aiken High School | 4A |
| 9/26/2025 | 7:30 PM | Andrews High School | Hanahan High School | 2A |
| 9/26/2025 | 7:30 PM | Baptist Hill High School | First Baptist Church School | 1A |
| 9/26/2025 | 7:30 PM | Barnwell High School | Silver Bluff High School | 2A |
| 9/26/2025 | 7:30 PM | Battery Creek High School | Whale Branch Early College High School | 3A |
| 9/26/2025 | 7:30 PM | Berea High School | Pickens High School | 4A |
| 9/26/2025 | 7:30 PM | Bishop England High School | Woodland High School | 4A |
| 9/26/2025 | 7:30 PM | Blacksburg High School | Gettys D Broome High School | 2A |
| 9/26/2025 | 7:30 PM | Blue Ridge High School | Landrum High School | 4A |
| 9/26/2025 | 7:30 PM | Boiling Springs High School | Eastside High School | 5A |
| 9/26/2025 | 7:00 PM | Brookland-Cayce High School | Midland Valley High School | 4A |
| 9/26/2025 | 7:30 PM | Atlantic Collegiate Academy | Oceanside Collegiate Academy | 2A |
| 9/26/2025 | 7:30 PM | Camden High School | Dreher High School | 3A |
| 9/26/2025 | 7:30 PM | Carvers Bay High School | Green Sea Floyds High School | 1A |
| 9/26/2025 | 7:30 PM | Central High School | Cheraw Senior High School | 2A |
| 9/26/2025 | 7:30 PM | Chapman High School | Belton-honea Path High School | 3A |
| 9/26/2025 | 7:30 PM | R B Stall High School | Waccamaw High School | 5A |
| 9/26/2025 | 7:30 PM | Christ Church Episcopal School | TBA | 3A |
| 9/26/2025 | 7:30 PM | Crescent High School | Liberty High School | 3A |
| 9/26/2025 | 7:30 PM | Cross High School | TBA | 1A |
| 9/26/2025 | 7:30 PM | D W Daniel High School | Seneca High School | 4A |
| 9/26/2025 | 7:30 PM | Dixie High School | TBA | 1A |
| 9/26/2025 | 7:30 PM | East Clarendon High School | Manning High School | 2A |
| 9/26/2025 | 7:30 PM | Fairfield Central High School | Andrew Jackson High School | 2A |
| 9/26/2025 | 7:30 PM | Fort Dorchester High School | White Knoll High School | 5A |
| 9/26/2025 | 7:30 PM | Fort Mill High School | Clover High School | 5A |
| 9/26/2025 | 7:30 PM | Military Magnet Academy | Bethune Bowman | 1A |
| 9/26/2025 | 7:30 PM | Gilbert High School | Aiken High School | 4A |
| 9/26/2025 | 7:30 PM | Gray Collegiate Academy | North Augusta High School | 4A |
| 9/26/2025 | 7:30 PM | Greenville Sr High School | J L Mann High School | 5A |
| 9/26/2025 | 7:30 PM | Greenwood High School | Hillcrest High School | 5A |
| 9/26/2025 | 7:30 PM | Hartsville High School | Wilson High School | 4A |
| 9/26/2025 | 7:30 PM | Hemingway High School | Lake View High School | 1A |
| 9/26/2025 | 7:30 PM | Hilton Head High School | Bluffton High School | 4A |
| 9/26/2025 | 7:30 PM | Indian Land High School | Rock Hill High School | 5A |
| 9/26/2025 | 7:30 PM | James Byrnes High School | Dorman High School | 5A |
| 9/26/2025 | 7:30 PM | Johnsonville High School | Hannah-pamplico High School | 1A |
| 9/26/2025 | 7:30 PM | W J Keenan High School | Chester High School | 3A |
| 9/26/2025 | 7:30 PM | Kingstree Senior High School | Lake City High School – SC | 2A |
| 9/26/2025 | 7:30 PM | Lake Marion High School & Technology Center | Allendale-fairfax High School | 2A |
| 9/26/2025 | 7:30 PM | Lakewood High School | Darlington High School | 4A |
| 9/26/2025 | 7:30 PM | Lancaster High School | Richland Northeast High School | 4A |
| 9/26/2025 | 7:30 PM | Lexington High School | Laurens District High School | 5A |
| 9/26/2025 | 7:30 PM | Lower Richland High School | Crestwood High School | 4A |
| 9/26/2025 | 7:30 PM | Lugoff-Elgin High School | Sumter High School | 5A |
| 9/26/2025 | 7:30 PM | May River High School | Georgetown High School | 4A |
| 9/26/2025 | 7:30 PM | Mid-carolina High School | Batesburg-leesville High School | 2A |
| 9/26/2025 | 7:30 PM | Mullins High School | Marion High School | 2A |
| 9/26/2025 | 7:30 PM | Myrtle Beach High School | Cane Bay High | 4A |
| 9/26/2025 | 7:30 PM | North Central High School | Buford High School | 2A |
| 9/26/2025 | 7:30 PM | Hunter-Kinard-Tyler Middle High School | Bamberg-Ehrhardt High School | 1A |
| 9/26/2025 | 7:30 PM | Northwestern High School | Catawba Ridge High School | 5A |
| 9/26/2025 | 7:30 PM | Pelion High School | Eau Claire High School | 2A |
| 9/26/2025 | 7:30 PM | Pendleton High School | Carolina High School | 3A |
| 9/26/2025 | 7:30 PM | Ridgeland Secondary Academy of Excellence | Hardeeville Junior/Senior High School | 1A |
| 9/26/2025 | 7:30 PM | Saluda High School | Newberry High School | 2A |
| 9/26/2025 | 7:30 PM | Scott’s Branch High School | St. John’s High School | 1A |
| 9/26/2025 | 7:30 PM | Southside Christian School | Carolina Forest High School | 3A |
| 9/26/2025 | 7:30 PM | Spartanburg High School | Gaffney High School | 5A |
| 9/26/2025 | 7:30 PM | Spring Valley High School | Blythewood High School | 5A |
| 9/26/2025 | 7:30 PM | St. James High School | Berkeley High School | 5A |
| 9/26/2025 | 7:30 PM | Summerville High School | Goose Creek High School | 5A |
| 9/26/2025 | 7:30 PM | Swansea High School | Columbia High School | 3A |
| 9/26/2025 | 7:30 PM | T L Hanna High School | Mauldin High School | 5A |
| 9/26/2025 | 7:30 PM | Travelers Rest High School | Greer Senior High School | 4A |
| 9/26/2025 | 7:30 PM | Union High School | Clinton High School | 3A |
| 9/26/2025 | 7:30 PM | Wade Hampton High School (Greenville) | Riverside High School | 5A |
| 9/26/2025 | 7:30 PM | Ware Shoals High School | TBA | 1A |
| 9/26/2025 | 7:30 PM | Westside High School | Abbeville High School | 4A |
| 9/26/2025 | 7:30 PM | Westwood High School | Ridge View High School | 4A |
| 9/26/2025 | 7:30 PM | Whitmire High School | Ridge Spring-Monetta High School | 1A |
| 9/26/2025 | 7:30 PM | Williston-elko High School | Fox Creek High School | 1A |
| 9/26/2025 | 7:30 PM | Woodmont High School | Easley High School | 5A |
| 9/26/2025 | 7:30 PM | Wren High School | Woodruff High School | 4A |
| 9/26/2025 | 7:30 PM | York Comprehensive High School | A C Flora High School | 4A |
| 9/27/2025 | 7:30 PM | Edisto High School | Denmark-Olar High School | 2A |
| 10/2/2025 | 7:30 PM | North Augusta High School | Aiken High School | 4A |
| 10/3/2025 | 7:30 PM | A C Flora High School | Lancaster High School | 4A |
| 10/3/2025 | 7:30 PM | Abbeville High School | Mc Cormick High School | 1A |
| 10/3/2025 | 7:30 PM | Airport High School | Midland Valley High School | 4A |
| 10/3/2025 | 7:30 PM | Andrews High School | Academic Magnet High School | 2A |
| 10/3/2025 | 7:30 PM | Aynor High School | Marlboro County High School | 3A |
| 10/3/2025 | 7:30 PM | Barnwell High School | Lake Marion High School & Technology Center | 2A |
| 10/3/2025 | 7:30 PM | Batesburg-leesville High School | Strom Thurmond High School | 2A |
| 10/3/2025 | 7:30 PM | Belton-honea Path High School | West Oak High School | 3A |
| 10/3/2025 | 7:30 PM | Blacksburg High School | Chesnee High School | 2A |
| 10/3/2025 | 7:30 PM | Blackville-hilda High School | Ridge Spring-Monetta High School | 1A |
| 10/3/2025 | 7:30 PM | Bluffton High School | Beaufort High School | 4A |
| 10/3/2025 | 7:30 PM | Blythewood High School | Lugoff-Elgin High School | 5A |
| 10/3/2025 | 7:30 PM | C A Johnson High School | Lewisville High School | 2A |
| 10/3/2025 | 7:30 PM | Branchville High SChool | Bethune Bowman | 1A |
| 10/3/2025 | 7:00 PM | Brookland-Cayce High School | Gray Collegiate Academy | 4A |
| 10/3/2025 | 7:30 PM | Atlantic Collegiate Academy | Marion High School | 2A |
| 10/3/2025 | 7:30 PM | Latta High School | Carvers Bay High School | 2A |
| 10/3/2025 | 7:30 PM | Buford High School | Central High School | 2A |
| 10/3/2025 | 7:30 PM | Calhoun Falls High School | Dixie High School | 1A |
| 10/3/2025 | 7:30 PM | Camden High School | South Pointe High School | 3A |
| 10/3/2025 | 7:30 PM | Cane Bay High | Lucy Beckham High School | 5A |
| 10/3/2025 | 7:30 PM | Carolina Forest High School | Socastee High School | 5A |
| 10/3/2025 | 7:30 PM | Carolina High School | Parkwood High School | 3A |
| 10/3/2025 | 7:30 PM | North Charleston High School | Battery Creek High School | 3A |
| 10/3/2025 | 7:30 PM | Cheraw Senior High School | Andrew Jackson High School | 4A |
| 10/3/2025 | 7:30 PM | Chester High School | Eau Claire High School | 2A |
| 10/3/2025 | 7:30 PM | Chesterfield High School | North Central High School | 2A |
| 10/3/2025 | 7:30 PM | Christ Church Episcopal School | St. Joseph’s Catholic School | 3A |
| 10/3/2025 | 7:30 PM | Clinton High School | Liberty High School | 3A |
| 10/3/2025 | 7:30 PM | Clover High School | Northwestern High School | 5A |
| 10/3/2025 | 7:30 PM | Crescent High School | Walhalla Senior High School | 3A |
| 10/3/2025 | 7:30 PM | Crestwood High School | Wilson High School | 4A |
| 10/3/2025 | 7:30 PM | D W Daniel High School | Berea High School | 4A |
| 10/3/2025 | 7:30 PM | Darlington High School | South Florence High School | 4A |
| 10/3/2025 | 7:30 PM | Denmark-Olar High School | Ridgeland Secondary Academy of Excellence | 1A |
| 10/3/2025 | 7:30 PM | Dillon High School | Loris High School | 3A |
| 10/3/2025 | 7:30 PM | Dorman High School | Boiling Springs High School | 5A |
| 10/3/2025 | 7:30 PM | Dutch Fork High School | Chapin High School | 5A |
| 10/3/2025 | 7:30 PM | Easley High School | Greenville Sr High School | 5A |
| 10/3/2025 | 7:30 PM | Eastside High School | Gaffney High School | 5A |
| 10/3/2025 | 7:30 PM | Fairfield Central High School | Mid-carolina High School | 2A |
| 10/3/2025 | 7:30 PM | Fort Dorchester High School | Ashley Ridge High | 5A |
| 10/3/2025 | 7:30 PM | Fountain Inn High School | Laurens District High School | 4A |
| 10/3/2025 | 7:30 PM | Fox Creek High School | TBA | 3A |
| 10/3/2025 | 7:30 PM | Military Magnet Academy | Baptist Hill High School | 1A |
| 10/3/2025 | 7:30 PM | Gettys D Broome High School | Woodruff High School | 3A |
| 10/3/2025 | 7:30 PM | Greer Senior High School | Pickens High School | 4A |
| 10/3/2025 | 7:30 PM | Hampton County High School | Edisto High School | 2A |
| 10/3/2025 | 7:30 PM | Hannah-pamplico High School | Lake View High School | 1A |
| 10/3/2025 | 7:30 PM | Hardeeville Junior/Senior High School | Bamberg-Ehrhardt High School | 1A |
| 10/3/2025 | 7:30 PM | Hillcrest High School | T L Hanna High School | 5A |
| 10/3/2025 | 7:30 PM | Hilton Head High School | Bishop England High School | 4A |
| 10/3/2025 | 7:30 PM | Hunter-Kinard-Tyler Middle High School | Wagener-Salley High School | 1A |
| 10/3/2025 | 7:30 PM | Indian Land High School | Nation Ford High School | 5A |
| 10/3/2025 | 7:30 PM | Irmo High School | Lexington High School | 5A |
| 10/3/2025 | 7:30 PM | James Island Charter High School | West Ashley High School | 5A |
| 10/3/2025 | 7:30 PM | J L Mann High School | Woodmont High School | 5A |
| 10/3/2025 | 7:30 PM | Johnsonville High School | Hemingway High School | 1A |
| 10/3/2025 | 7:30 PM | W J Keenan High School | Swansea High School | 3A |
| 10/3/2025 | 7:30 PM | Lake City High School – SC | Mullins High School | 2A |
| 10/3/2025 | 7:30 PM | Lamar High School | Mc Bee High School | 1A |
| 10/3/2025 | 7:30 PM | Lee Central High | TBA | 2A |
| 10/3/2025 | 7:30 PM | Lower Richland High School | Hartsville High School | 4A |
| 10/3/2025 | 7:30 PM | Manning High School | Kingstree Senior High School | 2A |
| 10/3/2025 | 7:30 PM | Mauldin High School | Greenwood High School | 5A |
| 10/3/2025 | 7:30 PM | May River High School | Colleton County | 4A |
| 10/3/2025 | 7:30 PM | Mountain View Preparatory | Union High School | 3A |
| 10/3/2025 | 7:30 PM | Newberry High School | Silver Bluff High School | 3A |
| 10/3/2025 | 7:30 PM | North Myrtle Beach High School | Conway High School | 5A |
| 10/3/2025 | 7:30 PM | Oceanside Collegiate Academy | Hanahan High School | 3A |
| 10/3/2025 | 7:30 PM | Pelion High School | Ninety Six High School | 2A |
| 10/3/2025 | 7:30 PM | Philip Simmons High School | Woodland High School | 3A |
| 10/3/2025 | 7:30 PM | Richland Northeast High School | Dreher High School | 4A |
| 10/3/2025 | 7:30 PM | Ridge View High School | Spring Valley High School | 5A |
| 10/3/2025 | 7:30 PM | Riverside High School | James Byrnes High School | 5A |
| 10/3/2025 | 7:30 PM | Rock Hill High School | Fort Mill High School | 5A |
| 10/3/2025 | 7:30 PM | Saluda High School | American Leadership Academy Lexington | 2A |
| 10/3/2025 | 7:30 PM | Seneca High School | Blue Ridge High School | 4A |
| 10/3/2025 | 7:30 PM | South Aiken High School | Gilbert High School | 4A |
| 10/3/2025 | 7:30 PM | Southside Christian School | Powdersville High School | 3A |
| 10/3/2025 | 7:30 PM | St. James High School | Myrtle Beach High School | 5A |
| 10/3/2025 | 7:30 PM | St. John’s High School | Cross High School | 1A |
| 10/3/2025 | 7:30 PM | Stratford High School | Berkeley High School | 5A |
| 10/3/2025 | 7:30 PM | Summerville High School | R B Stall High School | 5A |
| 10/3/2025 | 7:30 PM | Sumter High School | West Florence High School | 5A |
| 10/3/2025 | 7:30 PM | Timberland High School | Burke High School | 2A |
| 10/3/2025 | 7:30 PM | Travelers Rest High School | Pendleton High School | 4A |
| 10/3/2025 | 7:30 PM | Waccamaw High School | Georgetown High School | 3A |
| 10/3/2025 | 7:30 PM | Wade Hampton High School (Greenville) | Spartanburg High School | 5A |
| 10/3/2025 | 7:30 PM | Wando High School | Goose Creek High School | 5A |
| 10/3/2025 | 7:30 PM | Ware Shoals High School | Whitmire High School | 1A |
| 10/3/2025 | 7:30 PM | Westside High School | Southside High School | 4A |
| 10/3/2025 | 7:30 PM | White Knoll High School | River Bluff High School | 5A |
| 10/3/2025 | 7:30 PM | Williston-elko High School | Calhoun County High School | 1A |
| 10/3/2025 | 7:30 PM | Wren High School | Emerald High School | 4A |
| 10/7/2025 | 7:00 PM | South Carolina S.D. | TBA | 1A |
| 10/9/2025 | 7:30 PM | Aiken High School | Brookland-Cayce High School | 4A |
| 10/9/2025 | 7:30 PM | Spring Valley High School | Blythewood High School | 5A |
| 10/9/2025 | 7:30 PM | Wilson High School | Lower Richland High School | 4A |
| 10/10/2025 | 7:30 PM | Abbeville High School | Calhoun Falls High School | 1A |
| 10/10/2025 | 7:30 PM | Airport High School | Gray Collegiate Academy | 4A |
| 10/10/2025 | 7:30 PM | Andrew Jackson High School | Chesterfield High School | 2A |
| 10/10/2025 | 7:30 PM | Ashley Ridge High | R B Stall High School | 5A |
| 10/10/2025 | 7:30 PM | Aynor High School | Dillon High School | 3A |
| 10/10/2025 | 7:30 PM | Beaufort High School | Colleton County | 4A |
| 10/10/2025 | 7:30 PM | Berea High School | Seneca High School | 4A |
| 10/10/2025 | 7:30 PM | Bethune Bowman | St. John’s High School | 1A |
| 10/10/2025 | 7:30 PM | Blue Ridge High School | Greer Senior High School | 4A |
| 10/10/2025 | 7:30 PM | Boiling Springs High School | Wade Hampton High School (Greenville) | 5A |
| 10/10/2025 | 7:30 PM | Branchville High SChool | Baptist Hill High School | 1A |
| 10/10/2025 | 7:30 PM | Atlantic Collegiate Academy | Lake City High School – SC | 2A |
| 10/10/2025 | 7:30 PM | Burke High School | Philip Simmons High School | 2A |
| 10/10/2025 | 7:30 PM | Cane Bay High | Wando High School | 5A |
| 10/10/2025 | 7:30 PM | Carolina Forest High School | St. James High School | 5A |
| 10/10/2025 | 7:30 PM | Catawba Ridge High School | Indian Land High School | 4A |
| 10/10/2025 | 7:30 PM | Lucy Beckham High School | Stratford High School | 5A |
| 10/10/2025 | 7:30 PM | North Charleston High School | Oceanside Collegiate Academy | 3A |
| 10/10/2025 | 7:30 PM | Chesnee High School | Clinton High School | 3A |
| 10/10/2025 | 7:30 PM | Chester High School | Fairfield Central High School | 2A |
| 10/10/2025 | 7:30 PM | Conway High School | Myrtle Beach High School | 5A |
| 10/10/2025 | 7:30 PM | Cross High School | Scott’s Branch High School | 1A |
| 10/10/2025 | 7:30 PM | Dixie High School | Whitmire High School | 1A |
| 10/10/2025 | 7:30 PM | Edisto High School | Whale Branch Early College High School | 2A |
| 10/10/2025 | 7:30 PM | Fox Creek High School | Newberry High School | 3A |
| 10/10/2025 | 7:30 PM | Gaffney High School | James Byrnes High School | 5A |
| 10/10/2025 | 7:30 PM | Military Magnet Academy | CLEAR DOT CHARTER SCHOOL | 1A |
| 10/10/2025 | 7:30 PM | Goose Creek High School | Berkeley High School | 5A |
| 10/10/2025 | 7:30 PM | Great Falls High School | Lamar High School | 1A |
| 10/10/2025 | 7:30 PM | Greenwood High School | Greenville Sr High School | 5A |
| 10/10/2025 | 7:30 PM | Hanahan High School | Orangeburg-wilkinson High School | 3A |
| 10/10/2025 | 7:30 PM | Hannah-pamplico High School | Green Sea Floyds High School | 1A |
| 10/10/2025 | 7:30 PM | Hardeeville Junior/Senior High School | Denmark-Olar High School | 1A |
| 10/10/2025 | 7:30 PM | Hartsville High School | Crestwood High School | 4A |
| 10/10/2025 | 7:30 PM | Hemingway High School | Latta High School | 1A |
| 10/10/2025 | 7:30 PM | Hillcrest High School | J L Mann High School | 5A |
| 10/10/2025 | 7:30 PM | Hunter-Kinard-Tyler Middle High School | Calhoun County High School | 1A |
| 10/10/2025 | 7:30 PM | Kingstree Senior High School | East Clarendon High School | 2A |
| 10/10/2025 | 7:30 PM | Lake Marion High School & Technology Center | Hampton County High School | 2A |
| 10/10/2025 | 7:30 PM | Lake View High School | Carvers Bay High School | 1A |
| 10/10/2025 | 7:30 PM | Landrum High School | Blacksburg High School | 2A |
| 10/10/2025 | 7:30 PM | Lewisville High School | Lee Central High | 1A |
| 10/10/2025 | 7:30 PM | Lexington High School | Chapin High School | 5A |
| 10/10/2025 | 7:30 PM | Loris High School | Waccamaw High School | 3A |
| 10/10/2025 | 7:30 PM | Lugoff-Elgin High School | Ridge View High School | 5A |
| 10/10/2025 | 7:30 PM | Marlboro County High School | Georgetown High School | 3A |
| 10/10/2025 | 7:30 PM | Mauldin High School | Easley High School | 5A |
| 10/10/2025 | 7:30 PM | May River High School | Bishop England High School | 4A |
| 10/10/2025 | 7:30 PM | Mc Bee High School | C A Johnson High School | 1A |
| 10/10/2025 | 7:30 PM | Mc Cormick High School | Ware Shoals High School | 1A |
| 10/10/2025 | 7:30 PM | Dreher High School | Lancaster High School | 4A |
| 10/10/2025 | 7:30 PM | Mid-carolina High School | Columbia High School | 2A |
| 10/10/2025 | 7:30 PM | Midland Valley High School | Gilbert High School | 4A |
| 10/10/2025 | 7:30 PM | Mountain View Preparatory | Chapman High School | 3A |
| 10/10/2025 | 7:30 PM | Mullins High School | Manning High School | 2A |
| 10/10/2025 | 7:30 PM | Nation Ford High School | Rock Hill High School | 5A |
| 10/10/2025 | 7:30 PM | Northwestern High School | Fort Mill High School | 5A |
| 10/10/2025 | 7:30 PM | Ninety Six High School | Batesburg-leesville High School | 2A |
| 10/10/2025 | 7:30 PM | Wagener-Salley High School | Blackville-hilda High School | 1A |
| 10/10/2025 | 7:30 PM | Palmetto High School | Southside Christian School | 3A |
| 10/10/2025 | 7:30 PM | Powdersville High School | Christ Church Episcopal School | 3A |
| 10/10/2025 | 7:30 PM | Academic Magnet High School | Timberland High School | 3A |
| 10/10/2025 | 7:30 PM | Richland Northeast High School | A C Flora High School | 4A |
| 10/10/2025 | 7:30 PM | Ridgeland Secondary Academy of Excellence | Allendale-fairfax High School | 1A |
| 10/10/2025 | 7:30 PM | River Bluff High School | Irmo High School | 5A |
| 10/10/2025 | 7:30 PM | Riverside High School | Eastside High School | 5A |
| 10/10/2025 | 7:30 PM | Saluda High School | Pelion High School | 2A |
| 10/10/2025 | 7:30 PM | Silver Bluff High School | W J Keenan High School | 3A |
| 10/10/2025 | 7:30 PM | Socastee High School | North Myrtle Beach High School | 5A |
| 10/10/2025 | 7:30 PM | South Florence High School | Lakewood High School | 4A |
| 10/10/2025 | 7:30 PM | South Pointe High School | York Comprehensive High School | 4A |
| 10/10/2025 | 7:30 PM | Southside High School | Laurens District High School | 4A |
| 10/10/2025 | 7:30 PM | Spartanburg High School | Dorman High School | 5A |
| 10/10/2025 | 7:30 PM | St. Joseph’s Catholic School | Carolina High School | 3A |
| 10/10/2025 | 7:30 PM | Strom Thurmond High School | TBA | 2A |
| 10/10/2025 | 7:30 PM | Summerville High School | James Island Charter High School | 5A |
| 10/10/2025 | 7:30 PM | T L Hanna High School | Woodmont High School | 5A |
| 10/10/2025 | 7:30 PM | Travelers Rest High School | D W Daniel High School | 4A |
| 10/10/2025 | 7:30 PM | Union High School | Gettys D Broome High School | 3A |
| 10/10/2025 | 7:30 PM | Walhalla Senior High School | Pendleton High School | 3A |
| 10/10/2025 | 7:30 PM | West Ashley High School | Fort Dorchester High School | 5A |
| 10/10/2025 | 7:30 PM | West Florence High School | Blythewood High School | 5A |
| 10/10/2025 | 7:30 PM | West Oak High School | Crescent High School | 3A |
| 10/10/2025 | 7:30 PM | Westside High School | Emerald High School | 4A |
| 10/10/2025 | 7:30 PM | White Knoll High School | Dutch Fork High School | 5A |
| 10/10/2025 | 7:30 PM | Williston-elko High School | Ridge Spring-Monetta High School | 1A |
| 10/10/2025 | 7:30 PM | Woodland High School | Andrews High School | 2A |
| 10/10/2025 | 7:30 PM | Wren High School | Fountain Inn High School | 4A |
| 10/16/2025 | 6:00 PM | Chester High School | Columbia High School | 2A |
| 10/17/2025 | 7:30 PM | Aiken High School | Midland Valley High School | 4A |
| 10/17/2025 | 7:30 PM | Allendale-fairfax High School | Denmark-Olar High School | 1A |
| 10/17/2025 | 7:30 PM | Andrew Jackson High School | Central High School | 2A |
| 10/17/2025 | 7:30 PM | Ashley Ridge High | Summerville High School | 5A |
| 10/17/2025 | 7:30 PM | Bamberg-Ehrhardt High School | Ridgeland Secondary Academy of Excellence | 1A |
| 10/17/2025 | 7:30 PM | Baptist Hill High School | St. John’s High School | 1A |
| 10/17/2025 | 7:30 PM | Barnwell High School | Hampton County High School | 2A |
| 10/17/2025 | 7:30 PM | Batesburg-leesville High School | American Leadership Academy Lexington | 2A |
| 10/17/2025 | 7:30 PM | Berkeley High School | Wando High School | 5A |
| 10/17/2025 | 7:30 PM | Bishop England High School | Beaufort High School | 4A |
| 10/17/2025 | 7:30 PM | Blythewood High School | Sumter High School | 5A |
| 10/17/2025 | 7:30 PM | Boiling Springs High School | Spartanburg High School | 5A |
| 10/17/2025 | 7:30 PM | Columbia High School | Chester High School | 2A |
| 10/17/2025 | 7:30 PM | Branchville High SChool | Military Magnet Academy | 1A |
| 10/17/2025 | 7:30 PM | Atlantic Collegiate Academy | Manning High School | 2A |
| 10/17/2025 | 7:30 PM | Latta High School | Lake View High School | 2A |
| 10/17/2025 | 7:30 PM | Burke High School | Woodland High School | 2A |
| 10/17/2025 | 7:30 PM | Calhoun County High School | Blackville-hilda High School | 1A |
| 10/17/2025 | 7:30 PM | Calhoun Falls High School | Mc Cormick High School | 1A |
| 10/17/2025 | 7:30 PM | Carolina High School | Christ Church Episcopal School | 3A |
| 10/17/2025 | 7:30 PM | Lucy Beckham High School | Goose Creek High School | 5A |
| 10/17/2025 | 7:30 PM | Chapin High School | River Bluff High School | 5A |
| 10/17/2025 | 7:30 PM | Chapman High School | Union High School | 3A |
| 10/17/2025 | 7:30 PM | R B Stall High School | West Ashley High School | 5A |
| 10/17/2025 | 7:30 PM | Cheraw Senior High School | North Central High School | 4A |
| 10/17/2025 | 7:30 PM | Chesterfield High School | Buford High School | 2A |
| 10/17/2025 | 7:30 PM | Clinton High School | Landrum High School | 3A |
| 10/17/2025 | 7:30 PM | Colleton County | Bluffton High School | 4A |
| 10/17/2025 | 7:30 PM | Crescent High School | Belton-honea Path High School | 3A |
| 10/17/2025 | 7:30 PM | D W Daniel High School | Pickens High School | 4A |
| 10/17/2025 | 7:30 PM | Darlington High School | Hartsville High School | 4A |
| 10/17/2025 | 7:30 PM | Dutch Fork High School | Lexington High School | 5A |
| 10/17/2025 | 7:30 PM | Easley High School | Hillcrest High School | 5A |
| 10/17/2025 | 7:30 PM | East Clarendon High School | Mullins High School | 2A |
| 10/17/2025 | 7:30 PM | Emerald High School | Southside High School | 4A |
| 10/17/2025 | 7:30 PM | Fountain Inn High School | Westside High School | 4A |
| 10/17/2025 | 7:30 PM | Fox Creek High School | W J Keenan High School | 3A |
| 10/17/2025 | 7:30 PM | Gaffney High School | Riverside High School | 5A |
| 10/17/2025 | 7:30 PM | Georgetown High School | Loris High School | 3A |
| 10/17/2025 | 7:30 PM | Gilbert High School | Brookland-Cayce High School | 4A |
| 10/17/2025 | 7:30 PM | Gray Collegiate Academy | South Aiken High School | 4A |
| 10/17/2025 | 7:30 PM | Great Falls High School | C A Johnson High School | 1A |
| 10/17/2025 | 7:30 PM | Green Sea Floyds High School | Johnsonville High School | 1A |
| 10/17/2025 | 7:30 PM | Greenville Sr High School | Mauldin High School | 5A |
| 10/17/2025 | 7:30 PM | Hemingway High School | Carvers Bay High School | 1A |
| 10/17/2025 | 7:30 PM | Hunter-Kinard-Tyler Middle High School | Williston-elko High School | 1A |
| 10/17/2025 | 7:30 PM | Indian Land High School | TBA | 5A |
| 10/17/2025 | 7:30 PM | Irmo High School | White Knoll High School | 5A |
| 10/17/2025 | 7:30 PM | James Byrnes High School | Eastside High School | 5A |
| 10/17/2025 | 7:30 PM | James Island Charter High School | Fort Dorchester High School | 5A |
| 10/17/2025 | 7:30 PM | J L Mann High School | T L Hanna High School | 5A |
| 10/17/2025 | 7:30 PM | Eau Claire High School | Fairfield Central High School | 2A |
| 10/17/2025 | 7:30 PM | Lakewood High School | Lower Richland High School | 4A |
| 10/17/2025 | 7:30 PM | Lancaster High School | South Pointe High School | 4A |
| 10/17/2025 | 7:30 PM | Laurens District High School | Wren High School | 4A |
| 10/17/2025 | 7:30 PM | Lee Central High | Lamar High School | 2A |
| 10/17/2025 | 7:30 PM | Lewisville High School | Mc Bee High School | 1A |
| 10/17/2025 | 7:30 PM | Liberty High School | Chesnee High School | 2A |
| 10/17/2025 | 7:30 PM | Marion High School | Lake City High School – SC | 2A |
| 10/17/2025 | 7:30 PM | Marlboro County High School | Dillon High School | 3A |
| 10/17/2025 | 7:30 PM | May River High School | Hilton Head High School | 4A |
| 10/17/2025 | 7:30 PM | Dreher High School | A C Flora High School | 4A |
| 10/17/2025 | 7:30 PM | Myrtle Beach High School | Socastee High School | 4A |
| 10/17/2025 | 7:30 PM | Nation Ford High School | Catawba Ridge High School | 5A |
| 10/17/2025 | 7:30 PM | North Augusta High School | Airport High School | 4A |
| 10/17/2025 | 7:30 PM | North Myrtle Beach High School | Carolina Forest High School | 5A |
| 10/17/2025 | 7:30 PM | Oceanside Collegiate Academy | Battery Creek High School | 3A |
| 10/17/2025 | 7:30 PM | Wagener-Salley High School | Ridge Spring-Monetta High School | 1A |
| 10/17/2025 | 7:30 PM | Palmetto High School | Powdersville High School | 3A |
| 10/17/2025 | 7:30 PM | Pendleton High School | West Oak High School | 3A |
| 10/17/2025 | 7:30 PM | Academic Magnet High School | Philip Simmons High School | 2A |
| 10/17/2025 | 7:30 PM | Ridge View High School | West Florence High School | 5A |
| 10/17/2025 | 7:30 PM | Rock Hill High School | Northwestern High School | 5A |
| 10/17/2025 | 7:30 PM | Saluda High School | Ninety Six High School | 2A |
| 10/17/2025 | 7:30 PM | Seneca High School | Greer Senior High School | 4A |
| 10/17/2025 | 7:30 PM | St. James High School | Conway High School | 5A |
| 10/17/2025 | 7:30 PM | St. Joseph’s Catholic School | Southside Christian School | 3A |
| 10/17/2025 | 7:30 PM | Stratford High School | Cane Bay High | 5A |
| 10/17/2025 | 7:30 PM | Strom Thurmond High School | TBA | 2A |
| 10/17/2025 | 7:30 PM | Swansea High School | Silver Bluff High School | 3A |
| 10/17/2025 | 7:30 PM | Timberland High School | Andrews High School | 2A |
| 10/17/2025 | 7:30 PM | Travelers Rest High School | Blue Ridge High School | 4A |
| 10/17/2025 | 7:30 PM | Waccamaw High School | Aynor High School | 3A |
| 10/17/2025 | 7:30 PM | Wade Hampton High School (Greenville) | Dorman High School | 5A |
| 10/17/2025 | 7:30 PM | Walhalla Senior High School | Berea High School | 3A |
| 10/17/2025 | 7:30 PM | Ware Shoals High School | Dixie High School | 1A |
| 10/17/2025 | 7:30 PM | Westwood High School | Lugoff-Elgin High School | 4A |
| 10/17/2025 | 7:30 PM | Whale Branch Early College High School | Lake Marion High School & Technology Center | 2A |
| 10/17/2025 | 7:30 PM | Whitmire High School | Abbeville High School | 1A |
| 10/17/2025 | 7:30 PM | Wilson High School | South Florence High School | 4A |
| 10/17/2025 | 7:30 PM | Woodmont High School | Greenwood High School | 5A |
| 10/17/2025 | 7:30 PM | Woodruff High School | Mountain View Preparatory | 3A |
| 10/17/2025 | 7:30 PM | York Comprehensive High School | Camden High School | 4A |
| 10/18/2025 | 2:30 PM | Bethune Bowman | Scott’s Branch High School | 1A |
| 10/18/2025 | 3:00 PM | Orangeburg-wilkinson High School | North Charleston High School | 3A |
| 10/18/2025 | 2:00 PM | South Carolina S.D. | TBA | 1A |
| 10/23/2025 | 6:00 PM | Chester High School | Mid-carolina High School | 2A |
| 10/24/2025 | 7:30 PM | Abbeville High School | Dixie High School | 1A |
| 10/24/2025 | 7:30 PM | Aiken High School | Gray Collegiate Academy | 4A |
| 10/24/2025 | 7:30 PM | Andrews High School | Burke High School | 2A |
| 10/24/2025 | 7:30 PM | Aynor High School | Georgetown High School | 3A |
| 10/24/2025 | 7:30 PM | Bamberg-Ehrhardt High School | Allendale-fairfax High School | 1A |
| 10/24/2025 | 7:30 PM | Baptist Hill High School | Scott’s Branch High School | 1A |
| 10/24/2025 | 7:30 PM | Battery Creek High School | Orangeburg-wilkinson High School | 3A |
| 10/24/2025 | 7:30 PM | Beaufort High School | May River High School | 4A |
| 10/24/2025 | 7:30 PM | Belton-honea Path High School | Pendleton High School | 3A |
| 10/24/2025 | 7:30 PM | Berea High School | Travelers Rest High School | 4A |
| 10/24/2025 | 7:30 PM | Berkeley High School | Lucy Beckham High School | 5A |
| 10/24/2025 | 7:30 PM | Bethune Bowman | Cross High School | 1A |
| 10/24/2025 | 7:30 PM | Blacksburg High School | Clinton High School | 2A |
| 10/24/2025 | 7:30 PM | Blackville-hilda High School | Hunter-Kinard-Tyler Middle High School | 1A |
| 10/24/2025 | 7:30 PM | Blue Ridge High School | D W Daniel High School | 4A |
| 10/24/2025 | 7:30 PM | Bluffton High School | Bishop England High School | 4A |
| 10/24/2025 | 7:30 PM | Columbia High School | Eau Claire High School | 2A |
| 10/24/2025 | 7:00 PM | Brookland-Cayce High School | North Augusta High School | 4A |
| 10/24/2025 | 7:30 PM | Atlantic Collegiate Academy | East Clarendon High School | 2A |
| 10/24/2025 | 7:30 PM | Latta High School | Hannah-pamplico High School | 2A |
| 10/24/2025 | 7:30 PM | Buford High School | Cheraw Senior High School | 2A |
| 10/24/2025 | 7:30 PM | Calhoun Falls High School | Ware Shoals High School | 1A |
| 10/24/2025 | 7:30 PM | Camden High School | Lancaster High School | 3A |
| 10/24/2025 | 7:30 PM | Cane Bay High | Goose Creek High School | 5A |
| 10/24/2025 | 7:30 PM | Carolina Forest High School | Myrtle Beach High School | 5A |
| 10/24/2025 | 7:30 PM | Carvers Bay High School | Johnsonville High School | 1A |
| 10/24/2025 | 7:30 PM | Catawba Ridge High School | Rock Hill High School | 4A |
| 10/24/2025 | 7:30 PM | Central High School | Chesterfield High School | 2A |
| 10/24/2025 | 7:30 PM | Chapin High School | Irmo High School | 5A |
| 10/24/2025 | 7:30 PM | North Charleston High School | Hanahan High School | 3A |
| 10/24/2025 | 7:30 PM | Chesnee High School | Crescent High School | 2A |
| 10/24/2025 | 7:30 PM | Clover High School | Nation Ford High School | 5A |
| 10/24/2025 | 7:30 PM | Colleton County | Hilton Head High School | 4A |
| 10/24/2025 | 7:30 PM | Crestwood High School | Darlington High School | 4A |
| 10/24/2025 | 7:30 PM | Dillon High School | Waccamaw High School | 3A |
| 10/24/2025 | 7:30 PM | Dorman High School | Gaffney High School | 5A |
| 10/24/2025 | 7:30 PM | Dutch Fork High School | River Bluff High School | 5A |
| 10/24/2025 | 7:30 PM | Eastside High School | Wade Hampton High School (Greenville) | 5A |
| 10/24/2025 | 12:00 PM | Emerald High School | Fountain Inn High School | 4A |
| 10/24/2025 | 7:30 PM | Fort Dorchester High School | R B Stall High School | 5A |
| 10/24/2025 | 7:30 PM | Fort Mill High School | Indian Land High School | 5A |
| 10/24/2025 | 7:30 PM | Gettys D Broome High School | Mountain View Preparatory | 3A |
| 10/24/2025 | 7:30 PM | Gilbert High School | Airport High School | 4A |
| 10/24/2025 | 7:30 PM | Great Falls High School | Lewisville High School | 1A |
| 10/24/2025 | 7:30 PM | Green Sea Floyds High School | Hemingway High School | 1A |
| 10/24/2025 | 7:30 PM | Greenwood High School | J L Mann High School | 5A |
| 10/24/2025 | 7:30 PM | Hampton County High School | Whale Branch Early College High School | 2A |
| 10/24/2025 | 7:30 PM | Hartsville High School | Lakewood High School | 4A |
| 10/24/2025 | 7:30 PM | Hillcrest High School | Greenville Sr High School | 5A |
| 10/24/2025 | 7:30 PM | James Byrnes High School | Spartanburg High School | 5A |
| 10/24/2025 | 7:30 PM | James Island Charter High School | Ashley Ridge High | 5A |
| 10/24/2025 | 7:30 PM | W J Keenan High School | Newberry High School | 3A |
| 10/24/2025 | 7:30 PM | Lamar High School | C A Johnson High School | 1A |
| 10/24/2025 | 7:30 PM | Landrum High School | Liberty High School | 2A |
| 10/24/2025 | 7:30 PM | Lexington High School | White Knoll High School | 5A |
| 10/24/2025 | 7:30 PM | Loris High School | Marlboro County High School | 3A |
| 10/24/2025 | 7:30 PM | Lower Richland High School | South Florence High School | 4A |
| 10/24/2025 | 7:30 PM | Lugoff-Elgin High School | Spring Valley High School | 5A |
| 10/24/2025 | 7:30 PM | Manning High School | Marion High School | 2A |
| 10/24/2025 | 7:30 PM | Mauldin High School | Woodmont High School | 5A |
| 10/24/2025 | 7:30 PM | Mc Bee High School | TBA | 1A |
| 10/24/2025 | 7:30 PM | Mc Cormick High School | Whitmire High School | 1A |
| 10/24/2025 | 7:30 PM | Mid-carolina High School | Chester High School | 2A |
| 10/24/2025 | 7:30 PM | Midland Valley High School | South Aiken High School | 4A |
| 10/24/2025 | 7:30 PM | Mullins High School | Kingstree Senior High School | 2A |
| 10/24/2025 | 7:30 PM | North Central High School | Andrew Jackson High School | 2A |
| 10/24/2025 | 7:30 PM | North Myrtle Beach High School | St. James High School | 5A |
| 10/24/2025 | 7:30 PM | Ninety Six High School | American Leadership Academy Lexington | 2A |
| 10/24/2025 | 7:30 PM | Wagener-Salley High School | Williston-elko High School | 1A |
| 10/24/2025 | 7:30 PM | Palmetto High School | St. Joseph’s Catholic School | 3A |
| 10/24/2025 | 7:30 PM | Pelion High School | Batesburg-leesville High School | 2A |
| 10/24/2025 | 7:30 PM | Philip Simmons High School | Timberland High School | 3A |
| 10/24/2025 | 7:30 PM | Pickens High School | Seneca High School | 4A |
| 10/24/2025 | 7:30 PM | Powdersville High School | Carolina High School | 3A |
| 10/24/2025 | 7:30 PM | Ridge Spring-Monetta High School | Calhoun County High School | 1A |
| 10/24/2025 | 7:30 PM | Riverside High School | Boiling Springs High School | 5A |
| 10/24/2025 | 7:30 PM | Socastee High School | Conway High School | 5A |
| 10/24/2025 | 7:30 PM | South Pointe High School | Dreher High School | 4A |
| 10/24/2025 | 7:30 PM | Southside Christian School | Christ Church Episcopal School | 3A |
| 10/24/2025 | 7:30 PM | Southside High School | Wren High School | 4A |
| 10/24/2025 | 7:30 PM | St. John’s High School | Military Magnet Academy | 1A |
| 10/24/2025 | 7:30 PM | Strom Thurmond High School | Saluda High School | 2A |
| 10/24/2025 | 7:30 PM | Sumter High School | Ridge View High School | 5A |
| 10/24/2025 | 7:30 PM | Swansea High School | Fox Creek High School | 3A |
| 10/24/2025 | 7:30 PM | T L Hanna High School | Easley High School | 5A |
| 10/24/2025 | 7:30 PM | Wando High School | Stratford High School | 5A |
| 10/24/2025 | 7:30 PM | West Ashley High School | Summerville High School | 5A |
| 10/24/2025 | 7:30 PM | West Florence High School | Westwood High School | 5A |
| 10/24/2025 | 7:30 PM | West Oak High School | Walhalla Senior High School | 3A |
| 10/24/2025 | 7:30 PM | Westside High School | Laurens District High School | 4A |
| 10/24/2025 | 7:30 PM | Woodland High School | Academic Magnet High School | 2A |
| 10/24/2025 | 7:30 PM | Woodruff High School | Chapman High School | 3A |
| 10/24/2025 | 7:30 PM | York Comprehensive High School | Richland Northeast High School | 4A |
| 10/25/2025 | 7:30 PM | Edisto High School | Barnwell High School | 2A |
| 10/25/2025 | 7:30 PM | Hardeeville Junior/Senior High School | Branchville High SChool | 1A |
| 10/30/2025 | 7:30 PM | Airport High School | Brookland-Cayce High School | 4A |
| 10/30/2025 | 7:30 PM | Berkeley High School | Cane Bay High | 5A |
| 10/30/2025 | 7:30 PM | Lucy Beckham High School | Wando High School | 5A |
| 10/30/2025 | 7:30 PM | Fountain Inn High School | Southside High School | 4A |
| 10/30/2025 | 7:30 PM | Georgetown High School | Dillon High School | 3A |
| 10/30/2025 | 7:00 PM | Pelion High School | American Leadership Academy Lexington | 2A |
| 10/30/2025 | 7:30 PM | Philip Simmons High School | Andrews High School | 3A |
| 10/31/2025 | 7:30 PM | A C Flora High School | Camden High School | 4A |
| 10/31/2025 | 7:30 PM | Allendale-fairfax High School | Hardeeville Junior/Senior High School | 1A |
| 10/31/2025 | 7:30 PM | Andrew Jackson High School | Buford High School | 2A |
| 10/31/2025 | 7:30 PM | Batesburg-leesville High School | Saluda High School | 2A |
| 10/31/2025 | 7:30 PM | Battery Creek High School | Hanahan High School | 3A |
| 10/31/2025 | 7:30 PM | Bishop England High School | Colleton County | 4A |
| 10/31/2025 | 7:30 PM | Blackville-hilda High School | Williston-elko High School | 1A |
| 10/31/2025 | 7:30 PM | Blue Ridge High School | Berea High School | 4A |
| 10/31/2025 | 7:30 PM | Bluffton High School | May River High School | 4A |
| 10/31/2025 | 7:30 PM | Boiling Springs High School | James Byrnes High School | 5A |
| 10/31/2025 | 7:30 PM | C A Johnson High School | Lee Central High | 2A |
| 10/31/2025 | 7:30 PM | Calhoun County High School | Wagener-Salley High School | 1A |
| 10/31/2025 | 7:30 PM | Carolina High School | Southside Christian School | 3A |
| 10/31/2025 | 7:30 PM | Chapman High School | Gettys D Broome High School | 3A |
| 10/31/2025 | 7:30 PM | Academic Magnet High School | Burke High School | 3A |
| 10/31/2025 | 7:30 PM | Cheraw Senior High School | Chesterfield High School | 4A |
| 10/31/2025 | 7:30 PM | Chesnee High School | Landrum High School | 3A |
| 10/31/2025 | 7:30 PM | Christ Church Episcopal School | Palmetto High School | 3A |
| 10/31/2025 | 7:30 PM | Clover High School | Catawba Ridge High School | 5A |
| 10/31/2025 | 7:30 PM | Conway High School | Carolina Forest High School | 5A |
| 10/31/2025 | 7:30 PM | Crestwood High School | Lakewood High School | 4A |
| 10/31/2025 | 7:30 PM | Cross High School | Baptist Hill High School | 1A |
| 10/31/2025 | 7:30 PM | Denmark-Olar High School | Bamberg-Ehrhardt High School | 1A |
| 10/31/2025 | 7:30 PM | Dixie High School | Mc Cormick High School | 1A |
| 10/31/2025 | 7:30 PM | Easley High School | Greenwood High School | 5A |
| 10/31/2025 | 7:30 PM | East Clarendon High School | Marion High School | 2A |
| 10/31/2025 | 7:30 PM | Eastside High School | Dorman High School | 5A |
| 10/31/2025 | 7:30 PM | Fairfield Central High School | Columbia High School | 2A |
| 10/31/2025 | 7:30 PM | Fort Mill High School | Nation Ford High School | 5A |
| 10/31/2025 | 7:30 PM | Gaffney High School | Wade Hampton High School (Greenville) | 5A |
| 10/31/2025 | 7:30 PM | Goose Creek High School | Stratford High School | 5A |
| 10/31/2025 | 7:30 PM | Gray Collegiate Academy | Gilbert High School | 4A |
| 10/31/2025 | 7:30 PM | Greenville Sr High School | T L Hanna High School | 5A |
| 10/31/2025 | 7:30 PM | Greer Senior High School | D W Daniel High School | 4A |
| 10/31/2025 | 7:30 PM | Hannah-pamplico High School | Hemingway High School | 1A |
| 10/31/2025 | 7:30 PM | Hilton Head High School | Beaufort High School | 4A |
| 10/31/2025 | 7:30 PM | Irmo High School | Dutch Fork High School | 5A |
| 10/31/2025 | 7:30 PM | James Island Charter High School | R B Stall High School | 5A |
| 10/31/2025 | 7:30 PM | J L Mann High School | Mauldin High School | 5A |
| 10/31/2025 | 7:30 PM | Johnsonville High School | Latta High School | 1A |
| 10/31/2025 | 7:30 PM | Eau Claire High School | Mid-carolina High School | 2A |
| 10/31/2025 | 7:30 PM | Kingstree Senior High School | Atlantic Collegiate Academy | 2A |
| 10/31/2025 | 7:30 PM | Lake Marion High School & Technology Center | Edisto High School | 2A |
| 10/31/2025 | 7:30 PM | Lake View High School | Carvers Bay High School | 1A |
| 10/31/2025 | 7:30 PM | Lamar High School | Lewisville High School | 1A |
| 10/31/2025 | 7:30 PM | Lancaster High School | York Comprehensive High School | 4A |
| 10/31/2025 | 7:30 PM | Laurens District High School | Emerald High School | 4A |
| 10/31/2025 | 7:30 PM | Liberty High School | Blacksburg High School | 2A |
| 10/31/2025 | 7:30 PM | Loris High School | Aynor High School | 3A |
| 10/31/2025 | 7:30 PM | Manning High School | Lake City High School – SC | 2A |
| 10/31/2025 | 7:30 PM | Mc Bee High School | Great Falls High School | 1A |
| 10/31/2025 | 7:30 PM | Midland Valley High School | North Augusta High School | 4A |
| 10/31/2025 | 7:30 PM | Myrtle Beach High School | North Myrtle Beach High School | 4A |
| 10/31/2025 | 7:30 PM | Newberry High School | Swansea High School | 3A |
| 10/31/2025 | 7:30 PM | North Central High School | Central High School | 2A |
| 10/31/2025 | 7:30 PM | Northwestern High School | Indian Land High School | 5A |
| 10/31/2025 | 7:30 PM | Ninety Six High School | Strom Thurmond High School | 2A |
| 10/31/2025 | 7:30 PM | Orangeburg-wilkinson High School | Oceanside Collegiate Academy | 3A |
| 10/31/2025 | 7:30 PM | Pendleton High School | Crescent High School | 3A |
| 10/31/2025 | 7:30 PM | Pickens High School | Travelers Rest High School | 4A |
| 10/31/2025 | 7:30 PM | Ridge Spring-Monetta High School | Hunter-Kinard-Tyler Middle High School | 1A |
| 10/31/2025 | 7:30 PM | Ridge View High School | Blythewood High School | 5A |
| 10/31/2025 | 7:30 PM | River Bluff High School | Lexington High School | 5A |
| 10/31/2025 | 7:30 PM | Scott’s Branch High School | Military Magnet Academy | 1A |
| 10/31/2025 | 7:30 PM | Silver Bluff High School | Fox Creek High School | 3A |
| 10/31/2025 | 7:30 PM | Socastee High School | St. James High School | 5A |
| 10/31/2025 | 7:30 PM | South Aiken High School | Aiken High School | 4A |
| 10/31/2025 | 7:30 PM | South Florence High School | Hartsville High School | 4A |
| 10/31/2025 | 7:30 PM | South Pointe High School | Richland Northeast High School | 4A |
| 10/31/2025 | 7:30 PM | Spartanburg High School | Riverside High School | 5A |
| 10/31/2025 | 7:30 PM | Spring Valley High School | West Florence High School | 5A |
| 10/31/2025 | 7:30 PM | St. John’s High School | Branchville High SChool | 1A |
| 10/31/2025 | 7:30 PM | St. Joseph’s Catholic School | Powdersville High School | 3A |
| 10/31/2025 | 7:30 PM | Summerville High School | Fort Dorchester High School | 5A |
| 10/31/2025 | 7:30 PM | Timberland High School | Woodland High School | 2A |
| 10/31/2025 | 7:30 PM | Union High School | Woodruff High School | 3A |
| 10/31/2025 | 7:30 PM | Waccamaw High School | Marlboro County High School | 3A |
| 10/31/2025 | 7:30 PM | Walhalla Senior High School | Belton-honea Path High School | 3A |
| 10/31/2025 | 7:30 PM | Ware Shoals High School | Abbeville High School | 1A |
| 10/31/2025 | 7:30 PM | West Ashley High School | Ashley Ridge High | 5A |
| 10/31/2025 | 7:30 PM | Westwood High School | Sumter High School | 4A |
| 10/31/2025 | 7:30 PM | Whale Branch Early College High School | Barnwell High School | 2A |
| 10/31/2025 | 7:30 PM | White Knoll High School | Chapin High School | 5A |
| 10/31/2025 | 7:30 PM | Whitmire High School | CALHOUN FALLS CHARTER SCHOOL | 1A |
| 10/31/2025 | 7:30 PM | Wilson High School | Darlington High School | 4A |
| 10/31/2025 | 7:30 PM | Woodmont High School | Hillcrest High School | 5A |
| 10/31/2025 | 7:30 PM | Wren High School | Westside High School | 4A |
